ZipLine® Medical Receives India Regulatory Approval for Non-Invasive Zip® Skin Closure System

ZipLine® Medical, Inc., an innovator in skin closure, today announced Central Drugs Standard Control Organization (CDSCO) approval of its Zip® Surgical Skin Closure device in India. This clearance will give the company access to the $3.5 billion medical device market in India, including growing specialties where the Zip has shown significant clinical and economic benefits, such as total joint replacement in orthopedics, and Cesarean-section and hysterectomy in obstetrics and gynecology. The Zip is a non-invasive and easy to use skin closure device that replaces sutures, staples and glue for surgical incisions and lacerations. Clinical studies have demonstrated significant time savings and less procedure variability that can decrease hospital costs and improve efficiencies. Studies have also demonstrated fewer wound complications, and the comfortable and simple removal can reduce post-discharge home health and clinic visits that affect overall healthcare cost in a bundled care environment. A patented force distribution design results in secure wound closure, excellent scar quality and high patient satisfaction. The Zip’s micro-adjustability and reversibility provide surgeons with precise control during closure, and care teams with security that they can adjust closure post-surgery, if needed. Unlike staples or sutures, there are no skin punctures with the Zip that can create pathways for bacteria. The Zip’s benefits have been demonstrated in clinical studies in orthopedic total-joint arthroplasty, foot and ankle surgery, pediatric cardiothoracic surgery, electrophysiology and dermatology. In addition, clinical study results from the University of Florida demonstrated an 18 percentage point higher tissue perfusion rate versus baseline with the Zip compared to staples (p<0.001) after closure for total ankle replacement procedures. The results were presented in a poster at the American College of Foot and Ankle Surgeons (ACFAS) conference in Las Vegas in March. Jason Piraino, DPM, MS, FACFAS, who presented the results, commented, “Maintaining adequate perfusion is one of the most important factors in ensuring wound healing. High perfusion correlates to fewer complications, such as dehiscence and infection. The Zip demonstrated a significant perfusion advantage over staples in our study.”

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Zipline® Medical Receives CFDA Approval For Non-invasive Zip® Skin Closure System

ZipLine® Medical, Inc., an innovator in skin closure, today announced China Food and Drug Administration (CFDA) approval and commercial availability of its Zip® Surgical Skin Closure device in the region. This clearance will give the company access to the $543 million Chinese wound closure device market serving over 40 million procedures, including growing specialties where the Zip has shown significant benefit, such as orthopedics for total joint placement and obstetrics for Cesarean-section and hysterectomy procedures. ZipLine Medical recently featured the Zip at the prestigious 11th International Congress of the Chinese Orthopaedic Association, held in Beijing. The Zip is a non-invasive, efficient and easy to use wound closure device that replaces traditional sutures, staples and glue for surgical incisions and lacerations. It results in a comfortable, secure wound and the device’s unique force distribution system results in high patient comfort and excellent scar quality. The Zip’s micro-adjustability and eversibility provide surgeons with precise control and flexibility during closure. Because application and removal are simple, clinicians can delegate the closure task and, at the clinician’s discretion, patients may remove the Zip at home. Unlike staples or sutures, there are no skin punctures with the Zip, so scarring is minimal and there are no added pathways for bacteria to enter. The Zip’s benefits have been demonstrated in clinical studies in orthopedic total-joint arthroplasty, cardiothoracic surgery, electrophysiology and dermatology. “The non-invasive Zip closure is ideally suited for the healthcare market in China, in light of its large and growing procedure volume, need for cost-effective and efficient solutions, and appreciation of aesthetics,” said ZipLine Medical’s President and Chief Executive Officer John Tighe. “We look forward to working with our team of distribution partners across China to bring the speed, safety, comfort and convenience of Zip to Chinese patients.”

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GE, Samsung, SABIC Venture join China Materialia Fund II

Shanghai based venture capital firm China Materialia has launched a second venture capital fund China Materialia Fund II, with GE Ventures as the lead Limited Partner. Other corporate limited partners participating in the first closing include Samsung Ventures, SABIC Ventures,Chinese companies Levson and Tianjing Runfeng.

In a country where internet, mobile internet and consumer services have been the center-of-attention for venture capitalists, China Materialia stands out with its focus on “hard technologies”that encompass new materials, advanced manufacturing, energy and environment.Founded in 2010, China Materialia raised its first fund of 160 million RMB in2011, with a mission to look for “world-class” technologies that enable compelling solutions to world’s pressing problems. The China Materialia Fund I funded 10 companies, ranging from medical devices, Industrial internet, to digital oil field services.

China Materialia’s CEO Dr. Min Zhou said: “We are honored and excited to partner with world’s leading industrial companies to launch China Materialia Fund II. Compared to IT companies, innovations in materials or advanced manufacturing take significantly more money, time, and resources to reach commercial success. Partnering with multi-national companiesis not only beneficial, but also necessary. This venture illustrates the rising innovation level in the country, as well as the important role that China plays as a beachhead market for many of world’s hard-tech innovations.”

Commenting on investment in China Materialia Fund II, Dr. Karen Kerr, head of Advanced Manufacturing practice at GE Ventures said:“As part of our transformation to become the leading Digital Industrial Company, GE Ventures is excited to collaborate with China Materialia, Samsung and SABIC to continue fostering innovation in China. We are committed to working with the local entrepreneurial ecosystem to grow companies that advance industries and improve lives.”

Besides the corporate investors, China Materialia Fund II also received commitments from the Shanghai government, with Shanghai venture capital guidance fund, Shanghai Baoshan Investment Management Co. and Shanghai Baoshan Industrial Park Development Co all contributing.

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HomeGrid Forum names Xingtera as first certified silicon vendor based in China

HomeGrid Forum today announced that Xingtera’s XT1800 chipset has been awarded its prestigious certification, recognizing a high-performance product that allows networking over any form of cabling at a rate of 1 Gigabit per second — a direct result of Xingtera’s ongoing dedication to the development of the chipset.

“At HomeGrid Forum we champion industry certification programs, not only to ensure that high, minimum standards are met, but also to enable widespread interoperability — something we believe to be key to the success of,” commented Donna Yasay, President of HomeGrid Forum. “Naming Xingtera as the first certified vendor based in China is an important milestone and paves the way for other Chinese vendors. Xingtera’s achievement is particularly impressive because they have done so much in a relatively short space of time.”

As well as the development of its chipset, Xingtera has become a key player in promoting technology and networking products in China, which is an extremely competitive and busy market as China continues to dominate the global technology industry.

Speaking of the importance of the certification, Xingtera’s CEO and HomeGrid Forum’s marketing co-chair, Yuqing Niu said: “This accomplishment marks a new milestone in the history of Xingtera, and the entire ecosystem. Our customers will now be able to develop and deploy high-performance, reliable wireline communication systems in next-generation networked homes based on the certified chipset. Working with HomeGrid Forum is enabling Xingtera to drive the rapid deployment of technology, especially in China, which is a market with great growth potential for”

This week, Yuqing Niu will speak at Smart Summit Asia (30 November-1 December, Singapore) on a panel session titled: Identifying Key Technology Drivers for Wider Adoption of Connected Solutions, which takes place on Day 2 between 15:20-15:50pm. For more information on HomeGrid Forum please visit the

About HomeGrid Forum
HomeGrid Forum (HGF) is an industry alliance that brings together the world’s best in technology innovators, silicon vendors, system manufacturers and service providers to promote, a globally recognized gigabit home networking technology based on ITU-T standards. Over 70 members promote the global adoption of, a single unified, multi-sourced networking technology – over coax, copper pairs, powerline, and plastic optical fiber – while continuing to support HomePNA deployments and their transition to HomeGrid Forum provides silicon and system certification through a strict compliance and interoperability testing program. For more information on HomeGrid Forum, please visit our website at
Follow us on @homegrid_forum

About Xingtera
Xingtera was established in 2010 by industry veterans, with vision to become one of the most recognizable and brightest stars in the Communication IC market. As a fabless IC company, Xingtera focuses on developing disruptive technologies to address four large markets: Home Networking, IP Camera Connectivity, Next-gen Access Network Infrastructure and Internet of Things (IoT). Xingtera has been leading the effort in promoting technology and standardization in China with the HomeGrid Forum during the past five years. Now standard has reached the highest level (national level) in China as the Country’s accepted “smart home” wireline home network technology.

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China Materialia’s “Innovation China 2016” conference brings together government, venture capital, corporates and start-ups to discuss opportunities brought by “China Manufacturing 2025”

More than 300 people attended the third “Innovation China” conference held in Shanghai on Oct 14th.  China Materialia organizes annual “Innovation China” conference centered on “innovation and entrepreneurship”, each “Innovation China” conference invites thought leaders from academics, executives of Fortune 500 companies, start-ups, venture capitalists and government departments to discuss, debate and generate new ideas on latest trends on one industry sector. It is a platform for connecting MNCs and start-ups, Chinese and foreign enterprises, capital and technology.

Sponsored by GE, Innovation China 2016’s theme was “Advanced Manufacturing”, speakers included Ms. Ziying XU, Vice director of Shanghai Municipal Commission of Economic and Information, Christine Furstoss, Vice president of GE Global Research, Rajiv Singh, President of SABIC Ventures, Jiandang GU, CEO, Phoenix Contact China, Leo Wong, head of Bosch China Incubator, Karen Kerr, Senior Managing Director of GE Ventures. Six start-up companies in 3D printing, connected devices, and advanced materials also presented at the conference. The speakers collectively probed and shared insights on:
• What opportunities do start-ups have in core technology of advanced manufacturing (materials, technology, equipment), and in information fields (data, analytics, networking)?
• How should start-ups work with MNCs and realize open innovation for MNCs and open entrepreneurship for start-ups?
• What kind of opportunities and challenges are there for venture capital investing in this sector?
• What can Chinese start-ups and SMEs learn from abroad?
• In which areas can China become a leader worldwide? In technology or business model?

China Materialia Fund II also had a launch ceremony at the conference. The 400 million RMB China Materialia Fund II will invest in innovative start-ups in China in advanced materials, advanced manufacturing, energy and environment sectors. Min Zhou, CEO of China Materialia spoke at the conference and shared her perspectives on venture capital opportunities in advanced manufacturing sector.

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Zipline Skin Closure Device Shows Improved Scarring, Closure Time and Less Pain

ZipLine® Medical, Inc. an innovator in skin closure, today announced publication of positive results from the first prospective, randomized, controlled study of its Zip® Surgical Skin Closure in pediatric surgery. In the study, the Zip demonstrated significant improvements in scar appearance, efficiency and patient pain compared to suturing. Results were published online in the Annals of Thoracic Surgery.

The study of 214 pediatric patients undergoing cardiovascular surgery compared the Zip to continuous subcuticular polypropylene sutures for skin closure at three months. The study found:

• Significant improvement in scar appearance with the Zip, as evaluated by two plastic surgeons using the Vancouver Scar Scale (VSS) (p<0.017)

• Three times shorter skin closure time with the Zip (113.0 ± 9.1 seconds versus 375.9 ± 60.2 seconds, p<0.001)

• Significantly fewer patients cried or complained during removal of the Zip (7.1 percent versus 52.5 percent, p<0.001)

The article is entitled, “Randomized Study of a New Noninvasive Skin Closure Device for Use After Congenital Heart Operations.” The study was conducted at Gunma Children’s Medical Center, Shibukawa, and the Department of Cardiovascular Surgery, Kitasato University Hospital, Sagamihara, both in Japan. 
The authors concluded that, “our study showed that the (Zip) device has an excellent performance in improving the cosmetic appearance and reducing skin closure times.” They added, “use of this (Zip) device was not affected by the length of the wound or by different surgeons,” and “the tension can be adjusted multiple times according to the extent of the edema or wound healing after the operation.” 
The Zip is a non-invasive and easy to use device providing secure wound closure with uniformly distributed force along the length of the incision. Clinicians can adjust closure tension at any time peri- or post-procedure. Because closure and removal are simple, clinicians can delegate the task to a physician assistant or nurse, and patients may remove the Zip at home, if appropriate. The flexible design is not only comfortable for patients, but often enables them to make quicker progress in their recovery. Because there are no skin punctures with the Zip, scarring is minimal and there are no added channels for infection to enter.

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CM Portfolio Company Xingtera Successfully Completes Field Trials of Industry’s First Communication Solution for EVCS

Xingtera and Star Charge today jointly announced that they have completed their trial runs of the first ever high-speed powerline communication (PLC) based EVCS networking solution. The success of “EVConnect 2.0” field trials marks an important milestone for the powerline communication technology as well as the EVCS market. The combination of the wide-spread, real-world application of the powerline communication technology and the emerging, vast EVCS market makes it a profound achievement.

Xingtera is a communication IC, HW, and SW startup, founded by industry veterans at the heart of Silicon Valley in 2010 and financially backed by world leading venture capital firms. Star Charge is one of the Chinese leading EVCS operators, with more than 20,000 charging devices already deployed across China. The two companies started the strategic cooperation in 2015 to achieve a higher-level intelligent operations of EVCS and realize value-add services such as commercial advertisement display.

“EVConnect” is the broadband powerline networking solution developed by Xingtera to specifically address the need for the EVCS market. It provides communication access native to powerline to individual EV charging device and meets the demand for payment, remote EVCS management, and video downloading.

“EVConnect” is based on XT1200, Xingtera’s gigabit wireline communication ASIC. XT1200 complies with ITU-T’s standards, which include a series of protocols for long distance communication over existing wires such as powerline, coaxial cable, or telephone wire. Because of the advanced technology of, it has already been adopted by world leading telecom carriers such as China Telecom for home networking applications.

Since November 2015, “EVConnect 1.0” solution has been deployed in several EV charging stations across Shanghai, either by new installation or replacement of existing GPRS modules. With the new solution, network access can be obtained through existing powerline, indoor or outdoor. All charging stations’ network has been running smoothly since the installation. In cases where existing charging devices could not be utilized because of lack of network access, Xingtera’s solution has helped to bring those devices online.

Xingtera recently released “EVConnect 2.0,” which supports HD screens on top of charging devices, with the option of video downloading via powerline. In May 2016, a new-generation EVCS device with an integrated video screen, enabled by “EVConnect 2.0,” went online in Star Charge’s dealership in Yuqiao, Shanghai. Video displays of commercials during electrical vehicle charging were enthusiastically received by customers.

Star Charge was highly positive about the trial result. Ms. Shao Danwei, the chairwoman of Star Charge, said, “The successful field trial of ‘EVConnect 2.0’ shows that the solution is now ready for adoption for our charging stations. Compared to all existing networking solutions, Xingtera’s solution has its unique advantages. For example, when we used GPRS modules to connect EVCS to the Internet, the communication was not always reliable and broadband applications such as video downloading were not possible because of its low bandwidth. Now, with Xingtera’s solution, individual charging station is no longer limited by the strength of the wireless signal at its location. We actually save monthly data fee charge by removing GPRS modules. In the long run, Star Charge will select ‘EVConnect 2.0’ for future charging device deployment so that more bandwidth-hungry, value-add applications can be integrated to generate more profit for our company.”

Ms. Niu Yuqing, the chairwoman of Xingtera, said, “Looking at the result of the field trial, we are confident that ‘EVConnect 2.0’ has matured and is therefore ready for large-scale deployment. In the future of the EVCS market, communication plays the key role in more value-add business such as video commercial display. High-speed powerline communication technology fits this market perfectly because it provides stable network connection without additional wiring. Xingtera will keep upgrading the ‘EVConnect’ solution in order to satisfy increasing demand for all kinds of networking applications from next generation charging devices.”

“EVConnect” will address the networking issue for EVCS operators and help to realize intelligent operation platforms by enabling more related applications. In the same time, the solution will also bring enhanced experience to every EV owner during their charging process.
Xingtera Inc. is a contributor member of HomeGrid Forum. HomeGrid Forum (HGF) is an industry alliance that brings together the world’s best in technology innovators, silicon vendors, system manufacturers and service providers to promote, a globally recognized gigabit home networking technology based on ITU-T standards.

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CM Portfolio Zipline Medical raised $19 Million in financing

CM Portfolio Company ZipLine Medical, Inc. announced it has completed a $19 million round of financing. Proceeds from the financing will be used to accelerate worldwide commercialization activities for its Zip® Surgical Skin Closure products. The financing was led by new investor, MVM Life Science Partners LLP(“MVM”), a venture capital firm based in London and Boston, which invests broadly across the healthcare sector. China Materialia LLC also participated in the financing.

“I am impressed by the broad applicability as well as extensive clinical and economic benefits of ZipLine’s products. This makes ZipLine® a perfect fit in our healthcare investment portfolio,” said Bali Muralidhar, M.D., Ph.D., partner at MVM. “We are pleased to participate in this new infusion of capital to help carry the company to the next level of growth and commercial success,” added Stephen Reeders, M.D., Ph.D., managing partner at MVM. Both Dr Muralidhar and Dr Reeders have joined ZipLine’s Board of Directors.

“This financing allows us to further expand our global sales and marketing activities leveraging the favorable clinical study results and strong support from key opinion leaders among clinicians,” said John Tighe, President and CEO of ZipLine Medical.

Studies continue to demonstrate the clinical and economic benefits of the Zip® Surgical Skin Closure device. As presented at the 2015 ISTA Conference in Vienna, a recent knee arthroplasty study at Hospital for Special Surgery in New York showed that, compared to staples, patients with the Zip device had significantly fewer wound complications, required no home health nurse visit (for removal), and had no patient-reported problems or wound-related readmissions. Similarly, as presented at the 2015 APHRS Conference in Melbourne, Australia, a pacemaker study at UCSD in San Diego, CA, showed that, compared to sutures, patients with the Zip® device had significant procedure time savings, less variance in wound closure time, and suture-like cosmetic outcomes.

ZipLine® Medical (, founded by Amir Belson, M.D., and headquartered in Campbell, CA, is a medical device company that has developed cost-effective, noninvasive surgical skin closure devices for suture-like outcomes at the speed of staples. Over 25,000 surgical procedures have been performed worldwide with Zip® Surgical Skin Closure devices, and the Zip® is sold in over 30 countries. Because skin-closure is the common denominator of nearly all surgical procedures, Zip® Surgical Skin Closure devices have extensive applicability across multiple medical specialties. The Company’s addressable market opportunity is estimated at $4 billion worldwide. Zip® Surgical Skin Closure devices are classified by the U.S. FDA as ‘Class I, 510(k) Exempt’ and have received CE Mark.

ZipLine and Zip are registered trademarks of ZipLine Medical, Inc.

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Thingple signs contract with Baosteel Gas

Thingple has entered into a contract with Baosteel Gas to deploy an industrial gas cylinder management system based on UHF-RFID.

Baosteel Gas is one of the fastest-growing industrial gas companies in China. To ensure safety and track-ability of its gas cylinders, and to improve asset utilization rate and operation efficiency, Baosteel Gas looked worldwide for solutions based on electronic tagging of its cylinders. After rigorous selection process, Baosteel Gas selected Thingple as its exclusive partner in developing and deploying a SMART CYLINDER solution for its fleet of cylinders.

“We are delighted and honored to be selected as exclusive partner of Baosteel Gas to develop and deploy gas cylinder management system based on UHF-RFID. Thingple has spent last two years developing proprietary hardware and software platform, so that we could propose solutions that are modular, cost-effective, reliable and robust”. Chairman Dr. Zhou said, “RFID-based industrial gas cylinder tracking has been tempted by all major gas companies in the past, but none has commercialized in large scale because of difficulties in achieving 100% reliability in industrial setting. Thingple’s proprietary solution overcomes such difficulties with smartly-designed hardware and software”

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Two CEOs of China Materialia’s portfolio companies won China’s “National Thousand Talent” Recognition

Dr. Zhang Yan, the founder of Camray, and Dr. Dong Hu, the founder of iRock, both were selected in China’s “thousand talents program” for returnees in February 2015. Camray and iRock were funded by ChinaMaterialia as a lead investor.

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